Centers and Institutes
Brander Cancer Research Institute
Scientists study the basic mechanisms involved in control of cell proliferation, DNA repair and cell death as they relate to the differences between normal and cancer cells. They apply their discoveries and insights toward the development of more effective tools for the diagnosis, classification, and monitoring of treatment in individual patients.
- Develop tools for more accurate tumor diagnosis and prognosis leading to improved patient care;
- Train visiting scientists, postgraduate, graduate, and medical students in new drug evaluation, analysis of tumor kinetics and treatment, and cancer diagnosis and monitoring;
- Create an interdepartmental forum on cancer research.
Focuses on development of novel single cell assays to determine the mechanisms by which tumor cells differ from normal cells in how they control their growth; how cells repair damage to their genetic material, DNA; the development of sensitive tools to detect how cells identify and respond to various environmental insults that damage DNA; a method for investigating potential anti-aging molecules that reduce the likelihood of DNA damage; research into the cellular pathways of apoptosis, or cell death, and important cell response; and studies applying these assays in translational research to monitor individual patients' response to chemotherapy.
Zbigniew Darzynkiewicz, M.D., Ph.D., Director, 914-594-3794
Cardiovascular Research Institute
Researchers are focused on gaining a better understanding of myocardial cell death, and the contribution of necrosis and apoptosis to cardiac pathology and heart failure.
- To interfere with the death process and promote regeneration of infarcted myocardium.
- Includes investigations into myocardial necrosis, apoptosis, proliferation, and regeneration under the influence of native or introduced adult stem cells; the link between diabetes and cardiomyopathy; mechanisms involved in the onset, development and progression of congestive heart failure from a variety of causes; and the relationship between progressive increase in oxidative stress and myocardial cell death and cardiac dysfunction and aging.
Thomas Hintze, Ph.D.
Center for Disability & Health
To promote health and access to care for people with disabilities, prevent secondary conditions, and eliminate disparities between people with and without disabilities in the U.S.
- Include conducting interdisciplinary research, training, technical assistance, and educational activities related to disability and health.
- Includes community-based screening for autism, and interventions for children with developmental delays.
- Ansley Bacon, Ph.D., Director (914) 493-8204
Center for Disaster Medicine
To conduct interdisciplinary research, training, technical assistance, and educational activities related to emergency preparedness for disasters, terrorism, and public health emergencies.
- To serve as a multidisciplinary academic resource
- To facilitate emergency preparedness for the Hudson
- Valley, including preparedness for special populations, including children, the disabled, and the elderly
- To facilitate emergency health service delivery
- Preparedness for infants and children
- Preparedness for people with disabilities
- Preparedness for vulnerable populations
- Suburban regional surge capacity issues
- Emergency medical services disaster readiness
- Public health system preparedness
- Evidence-based benchmarks of preparedness
- Disaster medicine training and education
- David Markenson, M.D., Director, (914) 594-4323
Center for Long Term Care Research & Policy
The Center for Long Term Care Research and Policy is dedicated to improving the quality of long term care for all Americans. Using a multidisciplinary approach, the center engages in research, education and public policy development designed to address health care disparities, health care needs and caregiving across the lifespan and to promote fair and equitable financing of long term care in the United States.
- Address the social and economic inequalities in health among older people through a more robust understanding of the broader social determinants and financial components of our health care system.
- Improve the foundation of long term care through a better understanding and development of new policies to address the organization, financing and needs of the workforce of caregivers in both paid and unpaid sectors.
- Develop an integrated conceptual framework of long term care planning to reduce the limitations of disability for persons with developmental and intellectual disabilities across the lifespan.
- Food security, health and social service needs of homebound seniors in NYC
- Economic evaluation of a diabetes education and exercise intervention for seniors
- The impact of policy changes in Social Security on racial and ethnic health disparities
- The health effects of the Earned Income Tax Credit
- Ethical challenges of providing medical care to undocumented immigrants in the United States (in partnership with The Hastings Center)
- Post pediatric care transitions for children with special health care needs and developmental disabilities
- Patient and family needs: developing a casebook for end-of-life care
- Youth caregivers: contributions, consequences and economic impact
- Policy implications of an aging workforce
- End of life care for patients with dementia in the United States
- Patient assertiveness and their willingness to ask physicians to wash hands
- Health and wellness benefits of taiji & qigong among older people
Peter S. Arno, Ph.D., Director, (914) 594-4855
Center for Pediatric Hypotensive Disease
To study physiological processes related to orthostatic intolerance and other transient hypotensive states in children, adolescents, and young adults, including postural tachycardia syndrome (POTS), postural hyperpnea, and vasovagal faint.
- Studies focus on measures of central and peripheral blood flow and blood volume, and their control by the autonomic nervous system and factors which modulate autonomic regulation. Includes circulatory dysfunction in chronic fatigue syndrome, circulatory control in forms of orthostatic intolerance, studies of the interactions between chemoreceptors and baroreceptors in conscious humans, measurements and control of the sympathetic nervous system in childhood obesity, and the development of practical tools to assess microvascular function and fluid flow in patients with renal failure.
- Julian Stewart, M.D., Ph.D., Director, (914) 594-4370
Institute for Bioethics
To promote the care of patients as whole persons through research and education in bioethics. Utilizes an interdisciplinary approach incorporating philosophical, theological, legal, and empirical viewpoints.
- Includes ethics of end-of-life care, ethics education and professionalism, ethical issues surrounding cost-containment in health care, and ethical issues in research.
Institute for Minimally Invasive Surgery
To teach and train fellows and visiting surgeons in the techniques of minimally invasive surgery involving the use of videoscopically guided or assisted operative procedures.
- To improve overall operating room (OR) organization and efficiency
- To improve working relationships among hospital staff members and with representatives of technology manufacturers
- to facilitate research and development of new techniques and instruments
- to increase interest in and competence of OR personnel
- to streamline postoperative care
- Current research:
- Establishment of database registry providing comprehensive pre-, intra- and postoperative data on all gastric surgery performed by Institute faculty.
Ashutosh Kaul, M.D., Director, (914) 594-3241
Institute of Trauma & Emergency Care
To promote research, education, outreach, injury prevention, and improvement of patient care, in both pre-hospital and hospital settings, in the areas of trauma, emergency care, disaster preparedness, and care of the critically injured patient.
To research epidemiology, prevention, clinical, and basic science related to trauma, emergency, medicine, and critical care; and to provide Advanced Trauma Life Support (ATLS) courses to residents and interested physicians.
- Include creation of trauma and patient database repository containing refined data for research studies, and research by NYMC medical students in trauma, EMS, critical care, and injury prevention.
- Jay Yelon, D.O., Director, (914) 347-0162
NYMC-WAKF Renal Research Institute
To engage in biomedical research and to produce scholarly programs and publications in the field of nephrology and kidney functions, ailments, conditions, and treatments.
To facilitate translational laboratory-to-clinic research into early preclinical markers of endothelial dysfunction; to serve as a platform for educational activities including a renal fellowship training program, lecture series, and summer training for high school students; to serve as a site for annual international sabbatical professorship; and to provide summer training program for medical students.
- Includes seeking mechanistic characterization of physiological functions of the kidney; establishing pathophysiologic mechanisms of cardiovascular complications in patients with, and in animal models of, renal disease; and characterizing proteomic profile of different renal diseases such as renal transplant rejection.
Michael Goligorsky, M.D., Ph.D., Director, 914-594-4730