Victor A. Fried, Ph.D.

Program Director (M.S. & Ph.D.), Biochemistry and Molecular BiologyProgram Director (M.S. & Ph.D.), Cell Biology and AnatomyProfessor, Cell Biology and Anatomy & Pathology, Microbiology and Immunology Biomedical SciencesProfessor, Cell Biology and Anatomy & Pathology, Microbiology and Immunology School of Medicine

Education

  • B.S., Physical Chemistry, University of Chicago
  • Ph.D., Biochemistry, University of Oregon

Research

  • Intracellular protein trafficking
  • Protein degradation
  • Ubiquitin and the UPS
  • Cytoskeletal dynamics
  • Cell signaling; cancer
  • Neuroplasticity
  • Alzheimer’s Disease

Publications

  • Sullivan JA, Zhang XL, Sullivan AP, et. al. "Zinc enhances hippocampal long-term potentiation at CA1 synapses through NR2B containing NMDA receptors." PloS one, 13(11), (2018) e0205907. doi: 10.1371/journal.pone.0205907
  • Vinukonda G, Zia MT, Bhimavarapu BB, et. al. "Intraventricular hemorrhage induces deposition of proteoglycans in premature rabbits, but their in vivo degradation with chondroitinase does not restore myelination, ventricle size and neurological recovery." Experimental neurology, 247(), (2013) 630-44. doi: 10.1016/j.expneurol.2013.02.018
  • Tandeter H, Peleg R, Menahem S, et. al. "Teaching geriatric assessment in home visits: the family physician/geriatrician attachment." Teaching and learning in medicine, 15(2), (2003) 123-6.
  • Shah M, Patel K, Fried VA, et. al. "Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever." The Journal of biological chemistry, 277(47), (2002) 45662-9.
  • Guo GG, Patel K, Kumar V, et. al. "Association of the chaperone glucose-regulated protein 58 (GRP58/ER-60/ERp57) with Stat3 in cytosol and plasma membrane complexes." Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22(5), (2002) 555-63.
  • Buschmann T, Potapova O, Bar-Shira A, et. al. "Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress." Molecular and cellular biology, 21(8), (2001) 2743-54.
  • Ramanathan M, Hassanain M, Levitt M, et. al. "Oxidative stress increases ubiquitin--protein conjugates in synaptosomes." Neuroreport, 10(18), (1999) 3797-802.
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Teaching Responsibilities

  • Medical Histology and Cell Biology
  • Medical Neuroscience
  • Dental Histology and Cell Biology
  • Lecture Course in Histology
  • Laboratory Course in Histology
  • Quality Control in Cell Biology (Course Director)
  • Laboratory Course in Histology
  • Cell Biology
  • Responsible Conduct of Research (Co-course Director)
  • Novel Mechanisms in Protein Synthesis (Course Director)

Papers

65 peer-reviewed primary research papers with more than  10,000 citations, five of which have been cited more than 1,000 times.