Cell Biology Ph.D. Curriculum

This 2-semester course provides the student with an introduction to how organ systems, composed of cells and tissues, function in the body. The objective of this course is to provide students with an understanding of basic mammalian and human physiology. This course will cover the functions of mammalian organisms on several levels including organ systems, organs, cellular and subcellular levels. Organ systems covered in this 2-semester course include cardiovascular, respiratory, renal, endocrine, neural and gastrointestinal. Overall, students will gain a better understanding of body function. In addition, students will comprehend how certain basic and common pathological conditions alter human health and affect physiological function. This is a two-semester course, with part 1 running in the fall semester from August through December, and part 2 running from January through May.

In vitro and in vivo aspects of DNA, RNA and protein synthesis are covered in depth by instructors actively doing research in each of these areas. Special emphasis is placed on methods and techniques used to address key questions in the macromolecular processes of DNA replication and repair, RNA transcription and processing, protein synthesis, and post-translational modifications. Students are introduced to principles and applications of molecular techniques and new discoveries in the molecular biology of eukaryotes. Students are provided with a comprehensive reading list.

CBAM 1320 Lectures in Histology (3 credits)

Histology is the study at the microscopic level of the organization of cells in tissues and organs. This organization sets up the foundational principles underlying normal physiology and, from a clinical perspective, why alterations may lead to known pathologies. One goal is for students to appreciate why the spatial arrangement of tissues with organs elaborates physiologic function. During the course, the focus will be on the arrangement of tissues within various physiological systems, including cardiovascular, respiratory, gastroenterology, urinary, reproductive, endocrine, and sensory. Throughout students will be introduced to a variety of microscopic techniques, including light and electron microscopy and immunohistochemistry and immunofluorescence microscopy.

Laboratory sessions involve microscopic analysis of slides consisting of human and animal tissues and organs. Students will study tissue sections using microscopes and slides and will lead overview discussions prior to each laboratory session. Laboratory practical exams test knowledge of structural features of tissues and organs, and integrate functional and ultrastructural characteristics that are introduced in CBAM 1320.

This course will describe and relate neuroanatomical structures and their functional characteristics to the most common diseases of the nervous system. Particular attention is paid to the integration of neuroanatomy, neurophysiology, etiology, epidemiology and principle of treatment as pertinent for nervous system diseases. The goal is to understand neuroscientific basis of neurological diseases (central / peripheral nervous systems and skeletal muscle). This course runs for approximately 8 weeks.

Credits: 2-3 credits

Elective courses vary depending on your program. Students should consult with their graduate program director for available elective options.